Research

Medical Sciences

Title :

Development, Evaluation & Scale-UP of non-invasive & low cost rapid TB diagnostics

Area of research :

Medical Sciences, Life Sciences & Biotechnology

Focus area :

Point of care diagnostic tests and surveillance systems for common non-communicable and Infectious diseases

Principal Investigator :

Professor Rohit Srivastava, Professor, Department of Biosciences and Bioengineering, Indian Institute of Technology (IIT), Mumbai

Contact info :

Details

Executive Summary :

Around 10.4 million people FELL ILL FROM TB (WHO: 2016) (28,500 people per day). 1.8 million people died from TB including 400,000 with HIV + TB (over 4,900 people every day). 480 000 people have MDR TB in the world (2014). Diagnosis of human TB is extremely difficult, time-consuming and in-efficient. No efficient, cost effective tests are available for an early diagnosis of these infections. Therefore, rapid, economical, and improved TB diagnostic tests are urgently needed. The proposed tests (TB rapid serology tests, detection of LAM antigen in urine, MPT64 in sputum and EIOSPOT test) are rapid (20-25 minutes compared to 8 to 12 weeks for routine culture), low cost/affordable (compared to $10 for Xpert), do not require large equipment, mostly are point of care easy to use tests and only small amount of sample is needed.

Co-PI:

Dr. Vinay Saini, Senior Project Research Scientist, Department of Biosciences & Bioengineering, Indian Institute of Technology (IIT), Mumbai

Total Budget (INR):

2,30,40,000

Organizations involved