Research

Medical Sciences

Title :

Instrument-free Point-of-care Device for Detection of Pathogens and Antimicrobial resistance

Area of research :

Medical Sciences, Life Sciences & Biotechnology

Focus area :

Point of care diagnostic tests and surveillance systems for common non-communicable and Infectious diseases

Principal Investigator :

Prof Rinti Banerjee, Indian Institute of Technology (IIT), Mumbai

Contact info :

Details

Executive Summary :

Multidrug resistance in bacterial infections is increasing globally. The essential first step of rational antibiotic use is the diagnosis of whether the infection is of bacterial or viral origin and then identification of the bacteria. The existing methods for the distinguishing bacteria from viruses involve the use of expertise in microscopy, serology and microbiological culture. The project aims to develop and validate a point of care device for distinguishing bacteria from viruses, and the further classification and identification of bacteria into Gram positive or negative and a preliminary antimicrobial sensitivity to common drugs. This platform will help in screening causative organisms in infections and will be inexpensive, accessible, affordable, and easy to read. This will enable triage of those cases that require antibiotic therapy and those that require further referrals. Such a system will decrease the indiscriminate use of antibiotics and address the emergence of antimicrobial resistant strains globally.

Co-PI:

Dr B R Das, Advisor and Mentor - R&D and Molecular Pathology, SRL Diagnostics Ltd, Mumbai, Dr Rishi Adhikary, Department of Biosciences & Bioengineering, Indian Institute of Technology (IIT), Mumbai, Dr Biji Balakrishnan, Indian Institute of Technology (IIT), Mumbai, Dr. Sucheta P. Dandekar, Prof. & Head, Department of Biochemistry, Seth G. S. Medical College and KEM Hospital, Mumbai

Total Budget (INR):

1,49,97,000

Organizations involved