Research

Life Sciences & Biotechnology

Title :

In silico analysis of 10000 genomic sequences of COVID-19 around the world including India to identify genetic variability and potential molecular targets in virus and human

Area of research :

COVID-19 Research, Life Sciences & Biotechnology

Focus area :

Genome sequencing for COVID-19

Principal Investigator :

Dr Indrajit Saha, Assistant Professor, National Institute of Technical Teachers Training and Research (NITTTR), Kolkata

Timeline Start Year :

2020

Contact info :

Details

Executive Summary :

The study proposes to perform the in silico analysis of 10000 genomes around the globe including India of SARS-CoV-2 to identify the genetic variability in terms of mutation as missense, indel and silent.

Publications :

 
8

Outcome/Output:

As a result of this project, 30 MHC-I and 24 MHC-II restricted T-cell epitopes with 14 and 13 unique HLA alleles and 21 B-cell epitopes were identified for the 17 filtered conserved regions.

Organizations involved