Research

Medical Sciences

Title :

A Smartphone-Based Dark-Field Microscope for Point of Care (POC) Diagnosis of Blood-Cell Disorders in Lethal Diseases

Area of research :

Medical Sciences, Life Sciences & Biotechnology

Focus area :

Point of care diagnostic tests and surveillance systems for common non-communicable and Infectious diseases

Principal Investigator :

Prof Manabendra Chandra, Associate Professor, Department of Chemistry, Indian Institute of Technology (IIT), Kanpur

Contact info :

Details

Executive Summary :

The objective of the proposed research is to develop a dark-field microscopy-based smartphone attachment for accurate, quantitative and rapid diagnosis of human-blood samples. The proposed inexpensive device will have resolution comparable to laboratory microscopes and will work with just a finger-prick volume of unstained blood-cells. A downloadable and user-friendly custom app, which will guide any non-technical user in performing blood-test and analyzing the results step-by-step, will be designed. Abnormalities in number, size, shape, color-intensity of blood cells, and presence of target cells, fungi & parasites will be detected and the related diseases will be diagnosed through data mining. Our proposed device will help people in quick blood-analysis and diagnosis of various diseases like leukemia, sickle-cell anemia, thalassemia, dengue, malaria etc.

Co-PI:

Prof Raju K Gupta, Associate Professor, Department of Chemical Engineering, Indian Institute of Technology (IIT), Kanpur, Tanmoy Maiti, Assistant Professor, Department of MSE, Indian Institute of Technology (IIT), Kanpur, Manish Kulkarni, Indian Institute of Technology (IIT), Kanpur, Arnab Bhattacharya, Indian Institute of Technology (IIT), Kanpur, Anindita Gayen, Indian Institute of Technology (IIT), Kanpur, Dr. Sutapa Mondal, Indian Institute of Technology (IIT), Kanpur

Total Budget (INR):

1,06,06,000

Organizations involved