Technologies

Medical Sciences

Title:

Potent TLR9-Selective and TLR9/7 Dual Antagonists

Area:

Medical Sciences, Pharmaceutical Sciences

Focus Area:

Potent TLR9

Patent:

US10662177

Social Benefits:

Potent (nanomolar IC 50) small molecule inhibitora of TLR9 and TLR7: 'ABODINIBS' and 'ADADINIBS' , Demonstarated oral bioavailabity effiacy in human immune cells and pharmacokinetics in preclinal rodent model, Demonstrated efficacy in apreclinical model of psoriasis

Developing Agency:

CSIR-Indian Institute of Chemical Biology (IICB), West Bengal

Technology Readiness Index:

Technology Development

Email:

director@iicb.res.in
Website Link :http://www.iicb.res.in
Source (more info) :https://t.ly/l_sb

Brief Description

Description :

A series of potent inhibitors of toll-like receptor (TLR) 9 as well as dual antagonists of TLR9 and TLR with potential application in auto-immune disease and metabolic syndrome.

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