Research

Life Sciences & Biotechnology

Title :

Discovery of cannabinoids and their derivatives from Cannabis sativa for the management of chronic disease conditions like rheumatoid arthritis/neuropathic pain

Area of research :

Life Sciences & Biotechnology, Medical Sciences

Focus area :

Chronic disease management

Principal Investigator :

Dr Zabeer Ahmed, Scientist, CSIR-Indian Institute of Integrative Medicine (CSIR-IIIM), Jammu

Timeline Start Year :

2020

Timeline End Year :

2023

Contact info :

Details

Executive Summary :

Objective: Isolation of cannabinoids, semi-synthetic modifications to get derivatives and characterization using TLC, HPTLC, NMR. To investigate the nitric oxide and pro-inflammatory cytokine inhibition, in vitro and in vivo followed by anti-inflammatory activity testing of cannabinoids and their derivatives, in vivo. To test the potent cannabinoids & their derivatives in animal models of RA and NP.

Organizations involved