Research
Title : | Effect of 5% human albumin-based perioperative fluid therapy in perforation peritonitis patients undergoing emergency laparotomy: A randomized controlled trial |
Area of research : | Medical Sciences |
Focus area : | Fluid management |
Principal Investigator : | Dr Sulagna Bhattacharjee, Assistant Professor, All India Institute of Medical Sciences (AIIMS), Delhi |
Timeline Start Year : | 2022 |
Contact info : | bhattacharjee.sulagna85@gmail.com |
Associated Programme / Scheme : | Core Research Grant (CRG) |
Details
Executive Summary : | The primary objective of this study is to know the effect of 5% human albumin-based perioperative fluid therapy on postoperative endothelial glycocalyx shedding product, i.e. syndecan- 1, over isotonic balanced salt solutions. The secondary objective is to compare postoperative hyaluronan, heparan sulphate, ANP, TNF-a, IL-1, IL-6 and IL-10 in these two groups of patients. Along with the duration of ICU stay, duration of hospital stay and hospital mortality will be noted. |
Co-PI: | Dr Rahul Kumar Anand, Assistant Professor, All India Institute of Medical Sciences (AIIMS), Delhi |
Total Budget (INR): | 28,89,010 |
Organizations involved
Implementing Agency : | All India Institute of Medical Sciences (AIIMS), Delhi Funding Agency :Science and Engineering Research Board (SERB), Department of Science and Technology (DST) | |