Research

Pharmaceutical Sciences

Title :

Electro-conductive and immunomodulatory macroporous hydrogel conduit for faster spinal cord regeneration

Area of research :

Pharmaceutical Sciences

Focus area :

Medical Devices

Principal Investigator :

Dr. Akshay Srivastava, Associate Professor, National Institute of Pharmaceutical Education and Research, Ahmedabad

Timeline Start Year :

2022

Details

Executive Summary :

Spinal cord injury affects over a million people globally, with India having the highest incidence at 15000 annually. Current treatments are insufficient to improve neurological impairments and long-term survival rates. Biomaterial and stem cell therapies have been developed, but functional recovery is low due to limited microenvironment. A novel electro-conductive and immuno-modulatory graphene-incorporated collagen hydrogel is proposed to promote faster axonal regeneration and functional recovery, potentially shortening patients' stay on bed and reducing economic and social burden.

Co-PI:

Dr. Hemant Kumar, National Institute of Pharmaceutical Education and Research, Ahmedabad

Total Budget (INR):

58,27,905

Organizations involved