Research

Life Sciences & Biotechnology

Title :

Computational Repurposing of Drugs/Synthetic Compounds for Inhibiting RNA-dependent RNA polymerase (RdRp) in COVID-19 Infection in Humans

Area of research :

COVID-19 Research, Life Sciences & Biotechnology

Focus area :

Data Analytics, AI to model epidemic patterns and COVID-19 disease dynamics

Principal Investigator :

Dr. Rahul M. Shrivastava, Professor, Maulana Azad National Institute of Technology (MANIT), Bhopal

Timeline Start Year :

2020

Contact info :

Details

Outcome/Output:

The outcomes of proposed project will be sustainable in long-term as it will help in computational repurposing of peptide based drugs in coming days and will certainly reduce the time taken for the development of drugs. However, there is need of in vitro study to explore the possible factors acting as enhancers in the virus replication, and in vivo examination is necessary to check the efficacy and potency of the drug used at different stages of treatments. As specific cocktail of antiviral, anti-malarial and immune-suppressive drugs are given to patients, this study can helpful for researchers, scientists and doctors for target based therapy.

Organizations involved