Research
Title : | Exploring the clinically relevant notch1 mutations in south Indian T-acute lymphoblastic leukemia |
Area of research : | Medical Sciences |
Focus area : | Biochemistry |
Principal Investigator : | Dr. A. Srinivasan, Professor, All India Institute of Medical Sciences (AIIMS), New Delhi |
Timeline Start Year : | 2013 |
Timeline End Year : | 2016 |
Contact info : | srini@aiims.ac.in |
Details
Executive Summary : | Identified proteins from present study have been found play a crucial role in apoptosis. Identification of gentamicin-specific-binding eukaryotic proteins might underlie the nephrotoxicity, hepatotoxicity and neurotoxicity caused by this antibiotic and thus can lead to development of potential therapeutic approaches for improving the efficacy of the drug. |
Publications : | 1 |
Organizations involved
Implementing Agency : | All India Institute of Medical Sciences (AIIMS), New Delhi 110029 Funding Agency :Indian Council of Medical Research (ICMR), New Delhi | |