Research

Medical Sciences

Title :

Identification of diagnostic targets and therapeutic methods for infertility

Area of research :

Life Sciences & Biotechnology, Medical Sciences

Focus area :

Male factor infertility

Principal Investigator :

Dr Rajender Singh, Scientist, CSIR-Central Drug Research Institute (CSIR-CDRI), Lucknow

Timeline Start Year :

2020

Timeline End Year :

2023

Contact info :

Details

Executive Summary :

Objective: Undertaken transcriptome sequencing in sperm samples from infertile and fertile men; Undertake transcriptome sequencing in IVF failed and IVF successful sperm for; Trace strong miRNA candidates in peripheral blood of infertile individuals; Establish relationship in select paris of miRNAS and mRNAS with their roles in spermatogenesis; Investigation of transcriptome dynamics in the testicular germ cells for the identification of dynamics in gene expression; investigation of miRNAs in the testicular germ cells for the identification of key gene regulators of spermatogenesis.

Organizations involved