Research
Title : | In silico analysis of 10000 genomic sequences of COVID-19 around the world including India to identify genetic variability and potential molecular targets in virus and human |
Area of research : | COVID-19 Research, Life Sciences & Biotechnology |
Focus area : | Genome sequencing for COVID-19 |
Principal Investigator : | Dr Indrajit Saha, Assistant Professor, National Institute of Technical Teachers Training and Research (NITTTR), Kolkata |
Timeline Start Year : | 2020 |
Contact info : | indrajit@nitttrkol.ac.in |
Details
Executive Summary : | The study proposes to perform the in silico analysis of 10000 genomes around the globe including India of SARS-CoV-2 to identify the genetic variability in terms of mutation as missense, indel and silent. |
Publications : | 8 |
Outcome/Output: | As a result of this project, 30 MHC-I and 24 MHC-II restricted T-cell epitopes with 14 and 13 unique HLA alleles and 21 B-cell epitopes were identified for the 17 filtered conserved regions. |
Organizations involved
Implementing Agency : | National Institute of Technical Teachers Training and Research (NITTTR), Kolkata |
Funding Agency : | Department of Science and Technology (DST), Govt of India |