Technologies

Medical Sciences

Title:

Process for the Isolation of Organic Compounds Useful for the Treatment of Cancer

Area:

Medical Sciences

Focus Area:

Cancer Treatment

Patent:

US8637679

Social Benefits:

The main component plant is abundantly available plants throughout India. Novel purification protocol costs less and quick isolation. Total yield is high in EtOAc extract, which may be a useful for cancer treatment; Pharmacokinetics study indicated that the compounds are easily absorbable in blood stream and there is no production of secondary metabolites; Showed anti-cancer activity in low dose against glioma and cervical cancer cell lines Normal cells [heart, liver, muscle and peripheral blood mononuclear cells (PBMC)] showed minimum sensitivity by in vitro testing. Minimum toxic effects; This combination therapy reduced dose of highly toxic two known anticancer agent (cisplatin and paclitaxal); Multiple administration modes (oral, intravenous, intramuscular or subcutaneous rout) were available of these active components for the in vivo treatment.

Developing Agency:

CSIR-Indian Institute of Chemical Biology (IICB), West Bengal

Technology Readiness Index:

Lab Validation

Email:

director@iicb.res.in
Website Link :http://www.iicb.res.in
Source (more info) :https://t.ly/l_sb

Brief Description

Description :

Anti-cancer. The technology is very useful for the treatment of glioma and cervical cancers.

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