Life Sciences & Biotechnology
Title: | A Promising Therapeutic Lead from Medicinal Plant: Hope for Targeting Cancer and Cancer Stem like Cells |
Area: | Medical Sciences, Life Sciences & Biotechnology |
Focus Area: | Cancer Treatment |
Social Benefits: | In vitor studies with CM-5,Mechanism of Apotosis induced by CM-5, Toxicity of CM-5, In vivo and ex voivo studies with CM-5, Herbal extract enriched with CM-5 |
Developing Agency: | CSIR-Indian Institute of Chemical Biology (IICB), West Bengal |
Technology Readiness Index: | Market Launch |
Email: | director@iicb.res.in |
| Website Link : | http://www.iicb.res.in |
| Source (more info) : | https://t.ly/l_sb |
Brief Description
Description : | Abundantly available across India in all seasons Lead molecule: Carbazole Alkaloid (CM-5) medicinal value reported in Charaka Samhita. Non toxic to CD34+ progenitor cell, normal blood cells and astrocytes, normal lung/kidney cell lines from human to monkey. Showed NO acute and chronic toxicity towards normal mice
. Shows anti-proliferative activity against cancer cells(in vitro/ex vivo/ in vivo) |
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