US8153627: Quinazoline linked pyrrolo[2,1-c][1, 4]benzodiazepine hybrids as potential anticancer agents and process for the preparation thereof

The invention provides a compound of general formula 5, useful as potential antitumour agents against human cancer cell lines. The invention further provides a process for the preparation of pyrrolo[2,1-c][1,4]benzodiazepine hybrids of general formula (5): wherein n=3, 4, 5, 6, 8 and wherein R1 and R2 are selected from the group consisting of R1=H, R2=H or R1=CH3O, R2=CH3O or R1=CH3O and R2=C2H5O.