Research

COVID-19 Research

Title :

Design, fabrication and testing of portable, high-sensitivity aptasensors for one-step viral diagnostics

Area of research :

COVID-19 Research, Life Sciences & Biotechnology

Focus area :

COVID-19 Diagnostics

Principal Investigator :

Dr Murugan Ramalingam, Professor, Vellore Institute of Technology (VIT), Vellore

Timeline Start Year :

2020

Contact info :

Details

Executive Summary :

The main aim of this project proposal is to design, fabricate and test portable, high-sensitivity aptasensors as a diagnostic method to detect the presence of COVID-19.

Outcome/Output:

There is a pressing need to develop a more sensitive alternative method for diagnosing SARS-CoV-2. This project is planned in developing a potential solution, a concept of a portable, high-sensitive one-step diagnostic method exploiting the optical properties of gold nanoparticles (AuNP) conjugated with Angiotensin-converting enzyme 2 (ACE-2) aptamers when it binds with a target SARS-CoV-2 using Lateral flow assay (LFA).

Organizations involved