Patents

IN194988: A process for isolation of hyperforin

A process for isolation of hyperforin which comprises (i) extracting the dried plant material obtained from Hypericum perforatum L. with a hydrocarbon solvent such as herein described or acetone, (ii) concentrating the extract under vacuum to obtain residue, (iii) dissolving the above said residue in water if extraction is carried out in step (i) by using solvent selected from benzene, chloroform, dichloromethane or acetone and extracting the aqueous solution with a non polar solvent such as herein described, (iv) concentrating the alkane solvent extract to get the residue, (v) purifying the residue by High Performance Liquid Chromatography (HPLC) to get hyperforin of 99% purity, if desired freeze-drying the fraction collected from HPLC.

Filing Date: 28-02-2002

Issue Date: 17-03-2006

Applicant: Qazi Gn, Puri Sc, Handa G, Verma N, Anand R, Raina Rk, Bakshi Sk, Suri Op

Patent No: IN194988

Application No: 0180DEL2002

IPC Classification: A61K 35/78

Indian Classification: 55 E4

Country: India

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