IN234308: 2-alkyl 4,5 disubstituted 6- methoxyprimaquinone analogues

The invention relates to design and synthesis of potential antimalarial agents. These 8 - aminoquinoline class of compounds resulting from a unique and direct derivitazation at the C-2 position of the quinoline ring are expected to offer improvement over the existing chemotherapeutic approaches to malaria treatment by exerting their biological action on the parasite that may be present in the blood, tissues or blood and tissues of the host.