Patents

IN312298: Recyclable chiral catalyst for asymmetric nitroaldol reaction and process for the preparation thereof

The invention relates to preparation of highly efficient chiral recyclable homogeneous catalysts generated insitu by the reaction of chiral oligomeric [H4] ligands and a metal salt taken in 1:1 molar ratio for asymmetric nitroaldol reaction, wherein nitroaldol reactions of various aldehydes such as aromatic, aliphatic, ?,?-unsaturated aldehydes, alicyclic aldehydes and nitroalkenes were carried out to produce optically active ?-nitroalcohols in high yield and with moderate to excellent enantioselectivity (ee up to >95 %) in presence of a base and an optically active chiral recyclable homogeneous catalyst represented by the following formula (1).

Filing Date: 13-02-2001

Issue Date: 19-05-2006

Applicant: CSIR-Central Salt Marine Chemicals Research Institute (CSIR-CSMCRI), Bhavnagar

Patent No: IN312298

Application No: 0289DEL2013

Inventor(s): Kureshy Rukhsana Ilyas; Khan Noor -Ul Hasan; Abdi Sayed Hasan Razi; Bajaj Hari Chand; Roy Tamal; Das Anjan

IPC Classification: C07B

Country: India

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