Patents

A process for the preparation of ester derivatives of acyclic monoterpenoid

The present invention relates to a process for the preparation of ester derivatives of acyclic monoterpenoids. The present invention particularly relates to a process for the synthesis 3,7-dimethyl-6-octen-l-ol (citronellal) and 3,7-diemthyl-2,6-octadien-l-ol (geraniol) esters by reacting these alcohol and C3-C5-mono-carboxylic acids in the presence of a lipase catalyst. These esters are used as flavour and perfumery chemicals in the cosmetic industry for manufacturing the products of daily needs such as incense, dentifrice"s, perfumes, for flavouring confectionery, Pharmaceuticals, soap and dental preparations. The process steps are: reacting acyclic monoterpenoids such as herein described with C2-C5 mono carboxylic acid in the molar ratio of 1: 0.89 to 1:12 in presence of purified lipase catalyst, water at a temperature in the range of 25 to 35°C for a period of 4 to 6 hrs, stirring the reaction mixture, recovering the ester derivative from the reaction mixture by conventional methods using solvent.

Filing Date: 19-01-2001

Issue Date: 20-03-2008

Patent No: IN216970 [India]

Application No: 46/DEL/2001

Inventor(s): Ram Nath Das; Jiban Ch. Sarma Kataky

Licensing Option: Laboratory willing to jointly develop technology with industrial partner.

Implementing institute: CSIR-North East Institute of Science and Technology [CSIR-NEIST]

Funding agency: Council of Scientific and Industrial Research (CSIR)

IPC Classification: C07C 069/00

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