Patents

US10947248: 4beta-Amidotriazole Linked Podophyllotoxin Derivatives As Potential Anticancer Agents

The invention relates to a compound of general formula (A). The invention provides a synthesis of new 4?-amidotriazole linked podophyllotoxin derivatives of general formulae 8a-z to 9a-z useful as potential anticancer agents against human cancer cell lines and process for the preparation thereof. Wherein n=0, 1 and R1-R5=[H, CI, F, CH3, OCH3, 3,4(-OCH2O—), CF3, OCF3, m-OC6H5, OH]

Filing Date: 11-09-2018

Issue Date: 16-03-2021

Applicant: CSIR-Indian Institute of Chemical Technology (CSIR-IICT), Hyderabad

Patent No: US10947248

Application No: 16/084162

Inventor(s): Ahmed Kamal, Velma Ganga Reddy, Ayinampudi Venkata Subbarao, Syed Riyaz, Vadithe Lakshma Nayak, Shaik Taj

IPC Classification: C07D 493/04, A61P 31/12, A61P 35/00

Country: United States of America

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