Patents
The invention relates to an antioxidant compound having anti atherosclerotic effect and preparation thereof. The invention more particularly relates to the synthesis of TPP+ coupled esculetin (Mitochondria-targeted esculetin [Mitb-Esc]) followed by the biological evaluation of Mito-Esc for its ability to attenuate Angiotensin-11-induced atherosclerosis in apolipoproteinE knockout (ApoE/_) mice along with the endothelial cell age-delaying effects of Mito-Esc.