Life Sciences & Biotechnology
Title : | Plant-Based Rapidly Disintegrating Patches as a Treatment Modality for Oral Lichen Planus |
Area of research : | Life Sciences & Biotechnology |
Focus area : | Health, Life Science, Material Science & Engineering |
Principal Investigator : | Dr. Vivek Ghate M, Yenepoya University, Mangalore, Karnataka (575018) |
Timeline Start Year : | 2024 |
Timeline End Year : | 2027 |
Contact info : | vivekghate.yti@outlook.com,veenaomr@gmail.com |
Details
Executive Summary : | The study aims to develop a therapeutic modality for erosive oral lichen planus (OLP) using plant-extracts like guava, pomegranate, and okra. The extracts will be formulated into rapidly disintegrating patches (RDPs) using okra mucilage's mucoadhesive properties and excipients' super-disintegrating properties. The formulation will be tested for safety, non-irritancy, and efficacy in cell and tissue cultures from ATCC and biopsied samples from patients with OLP. The RDPs will be convenient, safer, and effective in reducing side-effects of conventional steroidal treatments for chronic management of OLP. |
Co-PI: | Dr. Veena K M, Yenepoya University, Mangalore, Karnataka (575018) |
Total Budget (INR): | 21,24,360 |
Organizations involved