Research
Title : | Design and Development of Catalytic Enyne Metathesis Type Cycloisomerization Reaction for the Synthesis of Functionalized Heterocycles, Polycyclic (hetero)aromatic Compounds and All Carbon Containing Tetrasubstituted Olefins |
Area of research : | Chemical Sciences |
Focus area : | Organic Synthesis and Catalysis |
Principal Investigator : | Dr. Ashok Kumar Basak, Banaras Hindu University, Varanasi, Uttar Pradesh |
Timeline Start Year : | 2024 |
Timeline End Year : | 2027 |
Contact info : | akb31377@gmail.com |
Equipments : | Recirculating chiller Vacuum pump Cryogenic bath Magnetic stirrer with thermostat |
Details
Executive Summary : | The proposed research project describes our working hypothesis and initial results towards the development of enyne metathesis type novel cycloisomerization chemistry using inexpensive metal triflate as a catalyst which will deliver highly functionalized heterocycles, polycyclic (hetero)aromatic compounds in step- and atom-economic manner. Our work also demonstrated a new avenue for the stereoselective synthesis of all carbon containing tetrasubstituted olefins. Our proposal shows the initial results of a novel domino intramolecular enyne metathesis-dipolar cycloaddition reaction which generates functionalized heterocyclic compounds. Development of a cascade 1,5-hydride transfer annulation-enyne metathesis reaction has also been included in the proposal. |
Total Budget (INR): | 45,76,264 |
Organizations involved
Implementing Agency : | Banaras Hindu University, Varanasi, Uttar Pradesh Funding Agency :ANRF/SERB | Source :Anusandhan National Research Foundation/Science and Engineering Research Board (SERB), DST 2023-24 | |