Research

Chemical Sciences

Title :

Transition metal-catalyzed fluorine insertion in small organic molecules

Area of research :

Chemical Sciences

Focus area :

Organic Chemistry, Catalysis

Principal Investigator :

Dr. Nilanjana Majumdar, CSIR-Central Drug Research Institute (CSIR-CDRI), Lucknow, Uttar Pradesh

Timeline Start Year :

2024

Timeline End Year :

2027

Contact info :

Details

Executive Summary :

A new concept has been proposed for the introduction of fluorine as well as various other fluorinated moieties in small organic molecules using transition-metal catalysis. The work will be explored for the introduction of “F”, “CF3”, “OCF3”, “SCF3” and more. For the asymmetric approach, to achieve the best results, various chiral ligands will be synthesized. The proposed concept would be able to avail important outcomes that would be useful for practical applications.

Total Budget (INR):

53,99,524

Organizations involved