Life Sciences & Biotechnology
Title : | Alteration of Ethylene signaling Pathway in Tomato for Geminivirus Tolerance |
Area of research : | Life Sciences & Biotechnology |
Focus area : | Plant Physiology |
Principal Investigator : | Dr. Pratibha Rawat, Jawaharlal Nehru University, New Delhi |
Timeline Start Year : | 2024 |
Timeline End Year : | 2026 |
Contact info : | pratibharawat175@gmail.com |
Details
Executive Summary : | Geminiviruses, characterized by circular, single-stranded DNA genomes, are phytopathogens that exploit plant hormones to propagate. One of the most destructive species, Tomato leaf curl Gujarat virus (ToLCGV), causes tomato leaf curl disease, a major constraint for tomato cultivation in India. RNA viruses can manipulate ethylene biosynthesis and signaling to positively regulate viral accumulation and infection. However, the pro-viral role of ethylene signaling in plant DNA viruses like Geminiviruses has not been reported. A project proposal aims to investigate the role of ACCO and ERF in ToLCGV pathogenesis and develop genome-edited lines of tomatoes targeting these genes for developing tolerance to ToLCGV. The expected outcome is understanding the molecular mechanism of ethylene signaling involved in geminivirus pathogenesis and developing geminivirus-resistant tomato plants. |
Total Budget (INR): | |
Organizations involved