Research

Life Sciences & Biotechnology

Title :

Deriving a pan-omics diagnostic pipeline for systems level immune health and therapeutic targeting in systemic autoimmunity

Area of research :

Life Sciences & Biotechnology, Medical Sciences

Focus area :

Systemic autoimmunity

Principal Investigator :

Dr Dipyaman Ganguly, Scientist, CSIR-Indian Institute of Chemical Biology (CSIR-IICB), Kolkata

Timeline Start Year :

2020

Timeline End Year :

2025

Contact info :

Details

Executive Summary :

Objective: 1: Development of a systems level 'immune wellness index' with potential for clinical translation as predictive signature of immune health. Objective 2: Gathering of novel emergent biological insights into the relationship of immune aberrations and gut dysbiosis and exploring the underlying mechanisms in two major autoimmune diseases, viz. SLE and RA. Objective 3: Exploring novel therapeutic targets in preclinical models of autoimmunity diseases.

Organizations involved