Life Sciences & Biotechnology
Title : | Fabrication of conjugates of supramolecular self-aggregated Structures: potentials in diagnosis and combination therapy |
Area of research : | Life Sciences & Biotechnology |
Focus area : | Oncology |
Principal Investigator : | Prof. Prasanta K Das, Professor, Indian Association for the Cultivation of Science (IACS), Kolkata |
Timeline Start Year : | 2021 |
Contact info : | bcpkd@iacs.res.in |
Associated Programme / Scheme : | Core Research Grant (CRG) |
Details
Executive Summary : | The proposal aimed to utilise combination therapy by means of exploiting the synergistic effect of cellular transporters as well as co-administration of two or more therapeutic agents (pro-drug-free drug, free drug-free drug, etc.) with a different mechanism of function for treating cancer. The developed self-assembled structures can serve as a functional table scaffold for augmented loading of chemotherapeutic agents while conjugation with highly fluorescent and photostable Carbon Dots (CDs) that may enable real-time tracking and locating of the drug-loaded conjugates as well as serve as a useful tool for pro-drug activation. |
Total Budget (INR): | 52,24,026 |
Organizations involved