Life Sciences & Biotechnology
Title : | Research in ASTHI: Pre-clinical development of CDRI optimized lead molecules as dual osteogenic and muscle anabolic agents |
Area of research : | Life Sciences & Biotechnology, Medical Sciences |
Focus area : | Osteoporosis |
Principal Investigator : | Dr Naibedya Chattopadhyay, Scientist, CSIR-Central Drug Research Institute (CSIR-CDRI), Lucknow |
Timeline Start Year : | 2020 |
Timeline End Year : | 2023 |
Contact info : | director@cdri.res.in |
Details
Executive Summary : | Objective: Nature-inspired synthesis of medicarpin and their derivativities as a novel dual-acting drug candidate for the treatment of osteoporosis: preclinical development. Evaluation of CDRI osteogenic lead medicarpin (water-soluble salt) in skeletal muscle atrophy. Engineered self-assembled composites bearing medicarpinl potential osteogenic agents for spatial drug targeting and bone regeneration. |
Organizations involved