Research

Medical Sciences

Title :

Research in ASTHI: Pre-clinical development of CDRI optimized lead molecules as dual osteogenic and muscle anabolic agents

Area of research :

Life Sciences & Biotechnology, Medical Sciences

Focus area :

Osteoporosis

Principal Investigator :

Dr Naibedya Chattopadhyay, Scientist, CSIR-Central Drug Research Institute (CSIR-CDRI), Lucknow

Timeline Start Year :

2020

Timeline End Year :

2023

Contact info :

Details

Executive Summary :

Objective: Nature-inspired synthesis of medicarpin and their derivativities as a novel dual-acting drug candidate for the treatment of osteoporosis: preclinical development. Evaluation of CDRI osteogenic lead medicarpin (water-soluble salt) in skeletal muscle atrophy. Engineered self-assembled composites bearing medicarpinl potential osteogenic agents for spatial drug targeting and bone regeneration.

Organizations involved

Implementing Agency :

CSIR-Central Drug Research Institute (CSIR-CDRI), Lucknow

Funding Agency :

Council of Scientific and Industrial Research (CSIR), Government of India

Source (more info) :

https://csirprojects.anusandhan.net/

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