Research
Title : | A unified Total Synthesis of Norditerpene Dilactones |
Area of research : | Chemical Sciences |
Principal Investigator : | Dr. Parthasarathi Subramanian, Indian Institute Of Technology Kanpur (IITK), Uttar Pradesh |
Timeline Start Year : | 2024 |
Timeline End Year : | 2027 |
Contact info : | parthas@iitk.ac.in |
Equipments : | Equipment's (Immersion cooler, Rotary evaporator, High vacuum pump, Magnetic stirrers and etc. |
Details
Executive Summary : | This proposal proposes a unified synthetic strategy for the asymmetric total synthesis of norditerpene dilactones. The route involves a cascade palladium-catalyzed dienylation, intramolecular Diels-Alder reaction, and sequential methylations. Substrate-controlled functionalization will ensemble the synthesis. The proposal could significantly impact the synthetic community by demonstrating an efficient method for synthesizing these biologically relevant and structurally complex natural products. |
Total Budget (INR): | 73,50,992 |
Organizations involved
Implementing Agency : | Indian Institute Of Technology Kanpur (IITK), Uttar Pradesh Funding Agency :Anusandhan National Rsearch Foundation (ANRF)/Science and Engineering Research Board (SERB) | Source :Anusandhan National Research Foundation/Science and Engineering Research Board (SERB), DST 2023-24 | |