Technologies

Chemical Sciences

Title:

Kojic acid production

Area:

Chemical Sciences

Status:

Presently viable culture is present in the lab and also deposited at MTCC possessing accession no. MTCC 5374. The compound, pure kojic acid is available in the lab.

Patent:

Patent filed

Developing Agency:

Council of Scientific & Industrial Research (CSIR) - National Institute of Oceanography (NIO)

Investment required (in INR):

Approx Rs. 1 lakh to obtain 500g of Kojic acid.

Brief Description

Description :

A method has been developed for production and purification of Kojic acid by fermentation of the marine fungus Aspergillus spp. and Penicillium spp. This organic acid continues to attract attention because of its economic potential in the field of medicine, food, cosmetic and agriculture. In the food industry, kojic acid is used as an inhibitor of polyphenol oxidase, an enzyme responsible for the blackening of agricultural products. In medicine, kojic acid is used mainly because it can eliminate free radicals and thus act as antioxidants. The use of kojic acid in cosmetics in the form of gels and soaps is to achieve skin lightening effect by inhibiting the enzyme tyrosinase thereby reducing the production of melanin formation. It also blocks the formation of pigmentation and evens out skin tone. At present it is introduced into various kinds of cosmetics like curing freckles, fighting age spots on the skin, acne, stretch marks due to obesity and pregnancy.

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