Research

Chemical Sciences

Title :

Divergent reactivity of dithioesters and thioamides: One-pot synthetic approach to functionalized heterocycles via recent strategies

Area of research :

Chemical Sciences

Focus area :

Organic Chemistry

Principal Investigator :

Prof. Maya Shankar Singh, Banaras Hindu University, Varanasi, Uttar Pradesh

Timeline Start Year :

2024

Timeline End Year :

2027

Contact info :

Details

Executive Summary :

The resurgence of interest in organic electrochemistry and photocatalysis has led to a boom in new synthetic methodologies and their mechanistic understandings. These techniques have become influential in modern synthetic chemistry due to their low energy consumption, mildness, and environmental friendliness. Electro-synthesis has led to several unprecedented methodologies, with the promise of achieving unique bond constructions that are not possible using established protocols. Synthetic chemists are motivated to exploit electro-synthesis in developing efficient strategies for potential organic small molecules. This field of research is growing in the context of global chemical research, and it is high time to undertake dedicated research to explore the area at large. The present proposal focuses on the usefulness and efficacy of electrochemical and photochemical strategies in developing advanced synthetic methods for promising heterocycles of societal value via C-H functionalization. The C-H functionalization technique has emerged as a fascinating strategy due to its numerous advantages. The field is expected to be considered a reliable and versatile platform by the broader scientific community for non-traditional bond construction in organic chemistry. It is high time to expand and explore the field by organic and medicinal chemists. The investigator is highly motivated to design and develop electro-synthetic/photochemical strategies for diverse series of heterocycles via C-H functionalization.

Co-PI:

Dr. Ashok Kumar Basak, Banaras Hindu University, Varanasi, Uttar Pradesh-221005

Total Budget (INR):

34,87,264

Organizations involved