Research

Chemical Sciences

Title :

Enantioselective Synthesis of Decahydroquinoline Cores of Lycopodium Alkaloids via Organocatalytic Diels Alder Reaction

Area of research :

Chemical Sciences

Focus area :

Organic Synthesis

Principal Investigator :

Dr. M Shiva Prasad, Central University Of Tamil Nadu, Thiruvarur, Tamil Nadu

Timeline Start Year :

2024

Timeline End Year :

2027

Contact info :

Details

Executive Summary :

The proposal aims to create a novel piperidine tethered exocyclic diene for the asymmetric D-A reaction through LUMO activation. The goal is to synthesize decahydroquinoline alkaloids with significant biological activities, particularly anti-Alzhemier activity, which could be useful in synthesizing lycopodium alkaloids and their analogs.

Total Budget (INR):

50,51,332

Organizations involved