Research

Life Sciences & Biotechnology

Title :

A bead-based assay kit for rapid detection of COVID -19 neutralising antibody

Area of research :

COVID-19 Research, Life Sciences & Biotechnology

Focus area :

Rapid detection kit for COVID-19

Timeline Start Year :

2020

Timeline End Year :

2020

Contact info :

Details

Executive Summary :

The project aims to develop bead-based assays that utilise recombinant protein immobilisation on beads with affinity tag or nanobody.

Outcome/Output:

Nanobody-mediated bead capture of orange fluorescent protein-tagged spike (SI) protein of SARS-CoV-2 showed rapid binding of soluble recombinant EGFP ACE2 that is inhibited by neutralising antibody. The assay is rapid, cost effective, sensitive and adaptable for multiple detection platforms.

Organizations involved