Patents

US9199930: Process for the preparation of (s)-2-ethyl-n-(1-methoxypropan-2-yl)-6-methyl aniline

Disclosed herein is a novel process for the preparation of (S)-2-ethyl-N-(1-methoxypropan-2-yl)-6-methyl aniline [(S)-1]. Particularly, the invention relates to the synthesis of (S)-2-ethyl-N-(1-methoxypropan-2-yl)-6-methyl aniline with excellent selectivity starting from commercially available enantiopure (R)-epichlorohydrin [(R)-2] via formation of aziridine intermediate [(S)-4].

Filing Date: 06-03-2015

Issue Date: 01-12-2015

Applicant: CSIR-National Chemical Laboratory (CSIR-NCL), Pune

Patent No: US9199930

Application No: 14/426452

Inventor(s): Muthukrishnan Murugan; Prashant Pramod Mujumdar

IPC Classification: C07C 213/02, C07D 203/14

Country: United States of America

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