Research
Title : | Analysis of inflammatory mediators involve in rheumatoid arthritis which may help in defining drug targets in north Indian population for the control of the disease |
Area of research : | Medical Sciences |
Focus area : | Biochemistry |
Principal Investigator : | Dr. Ameeta RaviKumar, Director, Savitribai Phule Pune University (SPPU), Pune, Maharashtra |
Timeline Start Year : | 2016 |
Timeline End Year : | 2017 |
Contact info : | ameeta@unipune.ac.in |
Details
Executive Summary : | We conclude that the 3T3L1 pre-adipocytes were successfully differentiated into adipocytes, forming more lipid droplets than the undifferentiated ones. Also confirmed that LipDH expression is more in the adipocytes than in the fibroblasts at the protein level. Finally, T. cordifolia leaf extract probably interferes with 3T3L1 adipogenesis and causes apoptosis of the cells, indicating that this extract may help down-regulate mammalian adipogenesis in the future |
Organizations involved
Implementing Agency : | Savitribai Phule Pune University (SPPU), Pune, Maharashtra, 411007 Funding Agency :Indian Council of Medical Research (ICMR), New Delhi | |