Title: | Mandibular bone augmentation with an indigenous developed novel fiber reinforced composite scaffold: A pilot clinical trial |
Area: | Medical Sciences |
Focus Area: | Devices and Diagnostics, Medical jaw implant, Biopharma |
Status: | Pre-commercilization stage (Phase I clinical trials are being conducted) |
Social Benefits: | Oral cancer is a major public health problem in India, where it ranks among the top three types of cancer. Although oral squamous cell carcinoma mainly occurs in oral soft tissues, involvement of jaw bones takes place in 12 out of 56 of the cases, necessitating surgical removal of jaw bone and adjacent areas, leading to functional and aesthetic deformity. Moreover, road traffic accidents are common in India, wherein orofacial trauma can occur, of which 50 needs reconstruction surgery. At present, vascularised fibula is the commonly used graft for mandibular reconstruction, but its less height restrict dental implant placement, which is a necessity for functional tooth restoration. The present strategy of mandible augmentation with fibrous composite scaffold will address this deficiency without the need of another surgery and approximately 50-60% of population affected with oral cancer mainly jaw bone will be benefited due to this. The method will not add high cost to the treatment, but tremendously increase the quality of the life of patients |
Developing Agency: | Amrita Vishva Vidyapeetham, Coimbatore, Tamil Nadu |
Technology Readiness Index: | TRL 6 |