Research
Title : | Drug repurposing against key COVID-19 drug targets using advance machine learning-based algorithms |
Area of research : | COVID-19 Research, Life Sciences & Biotechnology |
Focus area : | Drug repurposing |
Principal Investigator : | Dr Manoj Kumar Yadav, Assistant Professor, SRM University, Haryana |
Timeline Start Year : | 2020 |
Contact info : | manojiids@gmail.com |
Details
Executive Summary : | The aim of this study is to develop a model harnessing AI and ML approaches that is able to select and prioritise drugs according to descriptor properties in a lesser time. |
Outcome/Output: | The machine learning based model has successfully identified 75 compounds with an accuracy range of 70-100 per cent as active compounds against SARS-CoV-2 spike protein. All the screened active compound will further investigated using molecular docking protocols and MD simulation in the next part of the work. |
Organizations involved
Implementing Agency : | SRM University, Haryana Funding Agency :Department of Science and Technology (DST), Govt of India | |