Life Sciences & Biotechnology
Title : | Fabrication of three-dimensional nanocellulose-based multifunctional materials for tissue engineering and regenerative medicine applications |
Area of research : | Life Sciences & Biotechnology |
Focus area : | Health |
Principal Investigator : | Prof. Sabu Thomas, Mahatma Gandhi University, School of Chemical Sciences , Kottayam, Kerala, 686560 |
Timeline Start Year : | 2023 |
Timeline End Year : | 2026 |
Contact info : | sabuthomas@mgu.ac.in,nkkalarikkal@mgu.ac.in,rakhiraj09@gmail.com |
Details
Executive Summary : | Tissue engineering is a field of biomedical research that focuses on developing therapeutic procedures using functional materials that influence biological systems. Artificial extracellular matrices (ECMs) based on biomaterials and biopolymers can generate or stimulate specific biological functions by regulating cell behavior. However, challenges remain, such as the biomimicry of natural ECM architectures. The current project aims to develop nanocellulose-based bio-mimicking structures for tissue engineering and regenerative medicines. Nanocellulose, such as bacterial cellulose BC and plant cellulose, has unique properties and potential applications in wound dressing materials, burns, artificial skin, and tissue regeneration. The study aims to identify novel cellulose-producing bacterial strains and develop genetically engineered microbial strains for improved BC production. |
Co-PI: | Dr. Nandakumar Kalarikkal, Mahatma Gandhi University, School of Chemical Sciences , Kottayam Kerala, 686560, Dr. Raji V, Mahatma Gandhi University, Kerala, 686560 |
Total Budget (INR): | 31,45,688 |
Organizations involved