Earth, Atmosphere & Environment Sciences
Title : | Identification of bioactive non-ribosomal peptide molecules from bacterial isolates of Indian sector of Southern Ocean |
Area of research : | Earth, Atmosphere & Environment Sciences |
Focus area : | Ocean science |
Principal Investigator : | Dr.Tanu Jindal,Amity Institute of EnvironmentalToxicology, AmityUniversity,Sector-125,Noida,Uttar Pradesh, India |
Timeline Start Year : | 2022 |
Timeline End Year : | 2024 |
Details
Executive Summary : | 1. The varying levels of antibacterial activity exhibited by the extracts obtained from the mass-cultured and extracted bacteria will be useful in the development of new antimicrobial peptide. 2. • The identification of five confirmed organisms using 16s r RNA sequencing and phylogenetic data analysis will contribute to the taxonomic classification of bacteria in the Southern Ocean which can contribute to other biotechnological aspects of bacteria., 3. • The new data generated from the isolation and characterization of bacterial isolates from water and sediment samples in the Indian sector of the Southern Ocean are of great importance.4.• With the growing problem of antibiotic resistance, new antimicrobial agents are urgently needed, and marine bacteria have been shown to be a rich source of novel bioactive compounds with potential therapeutic applications. Therefore, the identification and characterization of these bacteria and their bioactive compounds can contribute significantly to drug discovery efforts.5. he ongoing experiments with purified fractions for the determination of antibacterial activity will provide more detailed information on the chemical nature and mechanism of action of the bioactive compounds obtained from these bacteria. This can provid the insights into the development of more effective and targeted therapies for bacterial infections. |
Co-PI: | Dr. Chauhan Abhishek, Amiety, |
Total Budget (INR): | 13,51,520 |
Organizations involved