Research
Title : | T-cell Immunology of COVID-19 infection and vaccination |
Area of research : | COVID-19 Research, Life Sciences & Biotechnology |
Focus area : | COVID-19 infection and vaccination |
Principal Investigator : | Dr Nimesh Gupta, Scientist, National Institute of Immunology (NII), New Delhi |
Timeline Start Year : | 2020 |
Contact info : | nimesh.gupta@nii.ac.in |
Details
Executive Summary : | This study aims to address crucial questions on the (i) quality and durability of T-cell immunity after infection and vaccination, (ii) vaccination outcome in virus infected individuals versus naïve population, and (iii) whether the immunity acquired after recovery from infection or vaccination will protect against the prevalent virus variants of concerns (VOCs). The major focus is to characterise the SARS-CoV-2 specific T-cell and antibody responses in a longitudinal infection or vaccination cohort. |
Publications : | 3 |
Outcome/Output: | The outcome of this work will provide (i) the crucial insight into the human T-cells responses to SARS-CoV-2 and COVID-19 vaccines, (ii) quality and durability of protective immunity after vaccination, (iii) vaccination outcome in virus infected individuals versus naïve population, and (iv) efficacy of vaccines against recently circulating or future variants of concerns (VOCs). |
Organizations involved
Implementing Agency : | National Institute of Immunology (NII), New Delhi Funding Agency : Science and Engineering Research Board (SERB), Department of Science and Technology (DST) Govt. of India | Department of Biotechnology (DBT) Govt. of India |