Life Sciences & Biotechnology
Title : | Understanding the cell death pathways induced by Mycobacteria infections |
Area of research : | Life Sciences & Biotechnology |
Focus area : | Apoptosis pathway |
Principal Investigator : | Dr Ashwani Kumar, Scientist, CSIR-Institute of Microbial Technology (CSIR-IMTECH), Chandigarh |
Timeline Start Year : | 2020 |
Timeline End Year : | 2023 |
Contact info : | ashwanik@imtech.res.in |
Details
Executive Summary : | Objective: To analyze the pattern of cell death (apoptotic, necrotic or autophagic) in response to Mtb infection (Mtb strains Ra and Rv; Mtb mutants ARD1, ARegX3, APhoP and M. bovis BCG). To analyze role of HO-1 in Mtb induced cell death .Specific Aim 3: To delineate the molecular mechanism of HO-1 mediated regulation of Mtb induced cell death. |
Organizations involved