An improved process for the preparation of 1-[2-dimethy lamino-(4-methoxy phenyel)-ethyl]cyclohexanol

The present invention relates to an improved process for the preparation of 1 -[2-dimethylamino-(4-methoxyhenyl) cyclohexanol of formula 1, The product is commonly known as Venlafaxine and also as effexor. In the process a one pot synthesis of compound of formula 1 from 1 [Cyano(4-methoxyphenyl) -cyclo-hexanol having formula 2 is carried out in presence of formylating agent such as formalin, catalyst-raney nickel and protic solvent. The compound of formula 2 is prepared by a single step conversion comprising the condensation of 4-methoxyphenylacetonitrile with cyclohexanone in the presence of a convenient base like sodium hydroxide