Patents

IN249712: A method for prevention of Cigarette Smoke induced protein oxidation

The invention provides a method for prevention of a major harmful oxidant, p-benzosemiquinone, of cigarette smoke. More particularly the invention provides antidotes for harmful effect caused by the harmful oxidant of cigarette smoke. Protein oxidation may be estimated by measuring the protein carbonyl formation from the incubation of protein and Cigarette Smoke (CS) solution or purified oxidant obtained from CS solution. Said protein carbonyl formation has been inhibited by adding a chemical compound in the incubation system of protein and purified oxidant obtained from CS solution. Said chemical compound is selected from a group consisting of ascorbic acid , sodium dithionate, tartaric acid, citric acid, oxalic acid, succinic acid, histidine, lysine, thiourea, glutathione, black tea extract, green tea extract, catechine, epigallocatechin for effective prevention of cigarette smoke induced protein oxidation. These chemical compounds are antidotes for cigarette smoke induced protein oxidation.

Filing Date: 18-05-2006

Issue Date: 04-11-2011

Applicant: CSIR-SGA

Patent No: IN249712

Application No: 1220DEL2006

Inventor(s): Indu Bhushan Chatterjee

IPC Classification: A24B

Country: India

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