Patents

IN300050: Process for the preparation of (s)-2-ethyl-n-(1-methoxypropan -2-yl)-6-methyl aniline

Disclosed herein a novel, process for the preparation of (S)-2-ethyl-N-(1-methoxypropan-2-yl)-6-methyl aniline [(S)-1]. Particularly, the invention relates to the synthesis of (S)-2-ethyL N-(1-methoxypropan-2-yt)-6-methyl aniline with excellent selectivity starting from commercially available enantiopure (R)-epichlorohydrin ((R)-2] via formation of aziridine intermediate [(S)-4].

Filing Date: 06-09-2012

Issue Date: 04-04-2014

Applicant: CSIR-National Chemical Laboratory (CSIR-NCL), Pune

Patent No: IN300050

Application No: 2768/DEL/2012

Inventor(s): Murugan, Muthukrishnan; Mujumdar, Prashant Pramod

IPC Classification: C07C

Country: India

Related Patents