IN349876: (E)-4-(4-acrylamidophenoxy)-n-methylpicolinamide conjugates as potential anticancer agents

The invention provides synthesis of new (E)-4-(4-acrylamidophenoxy)-n-methylpicolinamide conjugates of general formulae 6a-z to 7a-aj useful as potential anticancer agents against  human cancer cell lines and process for the preparation thereof. wherein R is selected from R1 to R5 is selected from the group  consisting of H, CI, F, Br, CH3, C2H5, CH(CH3)2, OCH3, CF3, OCF3, OH, NO2 or CN; X is selected from O, N or S.