IN363069: Synthesis and biological evaluation of 4?-amidotriazole linked podophyllotoxin derivatives as potential anticancer agents

The invention relates to a compound of general formula (A). The invention provides asynthesis of new 4?-amidotriazole linked podophyllotoxin derivatives of general formulae 8a-z to 9a-z useful as potential anticancer agents against human cancer cell lines and process for the preparation thereof. Wherein n = 0,1 and R1-R5 = [H, CI, F, CH3, OCH3, 3,4(-OCH2O-), CF3, OCF3, m-OC6H5, OH]