Patents

Pyrrolo[2,1-c][1,4]benzodiazepine compounds and processes for the preparation thereof

The present invention provides novel pyrrolo [2,1 c][1,4]benzodiazepine compounds.This invention also provides a process for the preparation of novel pyrrolo[2,1 c][1,4]benzodiazepine compounds.These novel pyrrolo [2,1-c][1,4]benzodiazepine compounds are useful as antitumor agents. It also provides a process for the preparation of 7-methoxy-8-{n-[4-(2-oxo-2H-4-chromenyl)piperazino]alkyl}-oxy-(11aS)-1,2,- 3,11a-5H-pyrrolo[2,1-c][1,4]benzodiazepin-5-one and 7-methoxy-8-{n-[4-(7-alkoxy-8-methyl-2-oxo-2H-4-chromenyl)piperazino]alky- l}-oxy-(11aS)-1,2,3,11a-5H-pyrrolo[2,1-c][1,4]. benzodiazepine-5-one with aliphatic chain length variations for these compounds.

Patent No: US7528128 [USA]; AU2003215810 [Australia]

Application No: 11/893,101 [USA]; AU20030215810 [Australia]

Inventor(s): Kamal, Ahmed; Babu, Ankati Hari; Ramana, Adhi Venkata; Bharathi, Earla Vijaya

Licensing Option: Laboratory willing to jointly develop technology with industrial partner.

Implementing institute: CSIR-Indian Institute of Chemical Technology [CSIR-IICT]

Funding agency: Council of Scientific and Industrial Research (CSIR)

IPC Classification: C07D 243/14, A61K 31/5517 [USA];A61K 31/5517, A61P35/00, C07D519/00 [Australia]

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