Research

Engineering Sciences

Title :

Polyphenylenediamine or silver hybrid based non-enzymatic glutamate sensor

Area of research :

Engineering Sciences

Focus area :

Material science

Principal Investigator :

Dr. Pradip Kar, Birla Institute of Technology, Mesra, Jharkhand

Timeline Start Year :

2024

Timeline End Year :

2027

Contact info :

Details

Executive Summary :

Glutamate, a non-essential amino acid, is a neurotransmitter with high concentrations in the body. It is produced from glucose and can cause neurotoxicity and neurological diseases. Abnormal levels of glutamate could indicate issues with glucose metabolism, making it interesting to analyze for neurological diseases and metabolic disorders. Monosodium glutamates are commonly used in fast foods and Chinese foods, but the Indian Preventions of Food Adulteration set a limiting value of 1%. sensitive and selective sensing of glutamate is relevant for clinical diagnosis, food industry, bio-processing, safety, drug discovery, environmental monitoring, fermentation monitoring, and renewable fuel cell development. Both enzymatic and non-enzymatic electrochemical methods are effective due to their high sensitivity, convenience, speed, and low cost. Non-enzymatic electrochemical sensors, such as those using electroactive polymers, have shown potential for improving stability, sensitivity, selectivity, reliability, and cost. The project aims to develop a non-enzymatic sensitive glutamate sensory system with high selectivity and sensitivity for applications in clinical diagnosis, food industry, bio-processing, safety, drug discovery, environmental monitoring, fermentation monitoring, and renewable fuel cell development.

Co-PI:

Dr. Vimal Kumarsingh Yadav, Birla Institute of Technology, Mesra, Ranchi, Jharkhand

Total Budget (INR):

26,56,016

Organizations involved